A Cryoablation Case Study
Case Study: The following is a 74 year old who underwent cryoablation of a 19 mm invasive ductal carcinoma. She remains cancer free 8 years after cryoablation.
Image 1: Photograph taken 3 years after cryoablation of a cancer in the upper outer right breast.
Cryoablation of a 19 mm invasive ductal carcinoma. 4 years of remission.
Image 2: Mammograms with arrows showing the cancer site in 2015 and same area of the breast in 2018, with no evidence of residual cancer, just 2 biopsy clips placed at the time of the initial diagnostic needle biopsy and 6-month post-cryoablation needle biopsy.
Image 2: Mammograms with arrows showing the cancer site in 2015 and same area of the breast in 2018, with no evidence of residual cancer, just 2 biopsy clips placed at the time of the initial diagnostic needle biopsy and 6-month post-cryoablation needle biopsy.
Image 4: Pathology results from original right breast needle biopsy and a repeat biopsy of the cancer site 6 months after cryoablation showing no residual cancer (see Image 5).
Image 5: Portion of pathology report showing
no residual tumor (cancer).
More Publications from Dr. Holmes
Cryoablation: A Minimally Invasive Alternative for Early-Stage Breast Cancer: 6-Year Outcomes of the FROST Clinical Trial
Cryoablation is emerging as a minimally invasive alternative to lumpectomy for select women with early-stage breast cancer. The FROST trial (NCT01992250) was a prospective, phase 2 multicenter study evaluating the outcome of cryoablation in the management of stage I, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-negative invasive ductal carcinoma.
Cryoablation: A Minimally Invasive Alternative for Early-Stage Breast Cancer: 6-Year Outcomes of the FROST Clinical Trial
Cryoablation is emerging as a minimally invasive alternative to lumpectomy for select women with early-stage breast cancer. The FROST trial (NCT01992250) was a prospective, phase 2 multicenter study evaluating the outcome of cryoablation in the management of stage I, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-negative invasive ductal carcinoma.
Cryoablation: A Minimally Invasive Alternative for Early-Stage Breast Cancer: 6-Year Outcomes of the FROST Clinical Trial
Cryoablation is emerging as a minimally invasive alternative to lumpectomy for select women with early-stage breast cancer. The FROST trial (NCT01992250) was a prospective, phase 2 multicenter study evaluating the outcome of cryoablation in the management of stage I, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-negative invasive ductal carcinoma.
A Non-Toxic Treatment for Breast Cancer - The Moss Report
Dr. Holmes explains how cryoablation—a targeted, minimally invasive technique that freezes tumors—can serve as an effective and less toxic alternative to traditional surgery and radiation.
A Non-Toxic Treatment for Breast Cancer - The Moss Report
Dr. Holmes explains how cryoablation—a targeted, minimally invasive technique that freezes tumors—can serve as an effective and less toxic alternative to traditional surgery and radiation.
A Non-Toxic Treatment for Breast Cancer - The Moss Report
Dr. Holmes explains how cryoablation—a targeted, minimally invasive technique that freezes tumors—can serve as an effective and less toxic alternative to traditional surgery and radiation.
FDA Approves ProSense Cryoprobe for Breast Cancer Cryoablation
By now, many of you have heard that the FDA has approved the use of the ProSense (IceCure) cryoprobe for the treatment of breast cancer with cryoablation. While this represents a major milestone, it is only the beginning of the process of achieving full Medicare and commercial insurance coverage for breast cancer cryoablation.
FDA Approves ProSense Cryoprobe for Breast Cancer Cryoablation
By now, many of you have heard that the FDA has approved the use of the ProSense (IceCure) cryoprobe for the treatment of breast cancer with cryoablation. While this represents a major milestone, it is only the beginning of the process of achieving full Medicare and commercial insurance coverage for breast cancer cryoablation.
FDA Approves ProSense Cryoprobe for Breast Cancer Cryoablation
By now, many of you have heard that the FDA has approved the use of the ProSense (IceCure) cryoprobe for the treatment of breast cancer with cryoablation. While this represents a major milestone, it is only the beginning of the process of achieving full Medicare and commercial insurance coverage for breast cancer cryoablation.
-1.png)
Freeze Away Cancer - Know Better Do Better Podcast
Featuring Dr. Dennis Holmes
Freeze Away Cancer - Know Better Do Better Podcast
Featuring Dr. Dennis Holmes
Freeze Away Cancer - Know Better Do Better Podcast
Featuring Dr. Dennis Holmes
L.A. Breast Chronicles - May Newsletter
Dr. Dennis R. Holmes unveils the FROST trial’s 5‑year results showing that tumor‑freezing (cryoablation) is as effective and safer than lumpectomy for Stage I breast cancer, with most patients avoiding lymph‑node surgery. The newsletter includes his ASBrS conference talk, a procedure video, and a thank‑you to the women who made these advances possible.
L.A. Breast Chronicles - May Newsletter
Dr. Dennis R. Holmes unveils the FROST trial’s 5‑year results showing that tumor‑freezing (cryoablation) is as effective and safer than lumpectomy for Stage I breast cancer, with most patients avoiding lymph‑node surgery. The newsletter includes his ASBrS conference talk, a procedure video, and a thank‑you to the women who made these advances possible.
L.A. Breast Chronicles - May Newsletter
Dr. Dennis R. Holmes unveils the FROST trial’s 5‑year results showing that tumor‑freezing (cryoablation) is as effective and safer than lumpectomy for Stage I breast cancer, with most patients avoiding lymph‑node surgery. The newsletter includes his ASBrS conference talk, a procedure video, and a thank‑you to the women who made these advances possible.
Society of Surgical Oncology Podcast
Featuring Dr. Dennis Holmes and Dr. Suzanne Klimberg, Speaking on Breast Cancer Ablation
Society of Surgical Oncology Podcast
Featuring Dr. Dennis Holmes and Dr. Suzanne Klimberg, Speaking on Breast Cancer Ablation
Society of Surgical Oncology Podcast
Featuring Dr. Dennis Holmes and Dr. Suzanne Klimberg, Speaking on Breast Cancer Ablation
L.A. Breast Chronicles - December Newsletter
L.A. Breast Chronicles - December Newsletter
L.A. Breast Chronicles - December Newsletter
Reducing the Risk of Needle Tract Seeding or Tumor Cell Dissemination during Needle Biopsy Procedures
Many women fear that breast needle biopsies increase the risk of cancer spread due to tumor cell displacement. Although evidence suggests minimal impact on breast cancer loco-regional recurrence or distant metastasis, technical modifications of needle biopsy procedures, including the use of cryoablation, can reduce the potential risks of breast needle-biopsy-induced cancer cell displacement to reduce patient fears of breast needle biopsy procedures.
Reducing the Risk of Needle Tract Seeding or Tumor Cell Dissemination during Needle Biopsy Procedures
Many women fear that breast needle biopsies increase the risk of cancer spread due to tumor cell displacement. Although evidence suggests minimal impact on breast cancer loco-regional recurrence or distant metastasis, technical modifications of needle biopsy procedures, including the use of cryoablation, can reduce the potential risks of breast needle-biopsy-induced cancer cell displacement to reduce patient fears of breast needle biopsy procedures.
Reducing the Risk of Needle Tract Seeding or Tumor Cell Dissemination during Needle Biopsy Procedures
Many women fear that breast needle biopsies increase the risk of cancer spread due to tumor cell displacement. Although evidence suggests minimal impact on breast cancer loco-regional recurrence or distant metastasis, technical modifications of needle biopsy procedures, including the use of cryoablation, can reduce the potential risks of breast needle-biopsy-induced cancer cell displacement to reduce patient fears of breast needle biopsy procedures.
A Cryoablation Case Study
The following is a 74 year old who underwent cryoablation of a 19 mm invasive ductal carcinoma. She remains cancer free 8 years after cryoablation.
A Cryoablation Case Study
The following is a 74 year old who underwent cryoablation of a 19 mm invasive ductal carcinoma. She remains cancer free 8 years after cryoablation.
A Cryoablation Case Study
The following is a 74 year old who underwent cryoablation of a 19 mm invasive ductal carcinoma. She remains cancer free 8 years after cryoablation.
Cryoablation Without Excision for Early‑Stage Breast Cancer: ICE3 Trial 5‑Year Follow‑Up on Ipsilateral Breast Tumor Recurrence
Breast cryoablation presents a promising alternative to surgery while offering the benefits of a minimally invasive procedure with minimal risks.
Cryoablation Without Excision for Early‑Stage Breast Cancer: ICE3 Trial 5‑Year Follow‑Up on Ipsilateral Breast Tumor Recurrence
Breast cryoablation presents a promising alternative to surgery while offering the benefits of a minimally invasive procedure with minimal risks.
Cryoablation Without Excision for Early‑Stage Breast Cancer: ICE3 Trial 5‑Year Follow‑Up on Ipsilateral Breast Tumor Recurrence
Breast cryoablation presents a promising alternative to surgery while offering the benefits of a minimally invasive procedure with minimal risks.
Breast Cancer Care During A Pandemic: An Opportune Time for Cryoablation?
Dr. Holmes is author of the newly published article, "Breast cancer care during a pandemic: an opportune time for cryoablation?" in Breast Cance...
Breast Cancer Care During A Pandemic: An Opportune Time for Cryoablation?
Dr. Holmes is author of the newly published article, "Breast cancer care during a pandemic: an opportune time for cryoablation?" in Breast Cance...
Breast Cancer Care During A Pandemic: An Opportune Time for Cryoablation?
Dr. Holmes is author of the newly published article, "Breast cancer care during a pandemic: an opportune time for cryoablation?" in Breast Cance...
Managing Your Breast Health During a Pandemic
The world is now abuzz with news about Coronavirus (COVID-19), the viral disease that has recently taken the world by storm.
Managing Your Breast Health During a Pandemic
The world is now abuzz with news about Coronavirus (COVID-19), the viral disease that has recently taken the world by storm.
Managing Your Breast Health During a Pandemic
The world is now abuzz with news about Coronavirus (COVID-19), the viral disease that has recently taken the world by storm.
De-escalating Breast Cancer Treatment—Mission Forward
This month’s newsletter draws attention to a recent JAMA Oncology editorial, De-escalating Breast Cancer Surgery—Where is the Tipping Point (Dec...
De-escalating Breast Cancer Treatment—Mission Forward
This month’s newsletter draws attention to a recent JAMA Oncology editorial, De-escalating Breast Cancer Surgery—Where is the Tipping Point (Dec...
De-escalating Breast Cancer Treatment—Mission Forward
This month’s newsletter draws attention to a recent JAMA Oncology editorial, De-escalating Breast Cancer Surgery—Where is the Tipping Point (Dec...
Understanding and Harnessing the Immune Effects of Cryoablation: A Work in Progress
Apart from the appeal of cryoablation as a minimally invasive alternative to surgery, many women are drawn to cryoablation because of its...
Understanding and Harnessing the Immune Effects of Cryoablation: A Work in Progress
Apart from the appeal of cryoablation as a minimally invasive alternative to surgery, many women are drawn to cryoablation because of its...
Understanding and Harnessing the Immune Effects of Cryoablation: A Work in Progress
Apart from the appeal of cryoablation as a minimally invasive alternative to surgery, many women are drawn to cryoablation because of its...
Cryoablation - Desert Sun: Letter to the editor
This letter to the editor was offered in response to a November 2019, Desert Sun article regarding a surgeon who was placed on probation by the...
Cryoablation - Desert Sun: Letter to the editor
This letter to the editor was offered in response to a November 2019, Desert Sun article regarding a surgeon who was placed on probation by the...
Cryoablation - Desert Sun: Letter to the editor
This letter to the editor was offered in response to a November 2019, Desert Sun article regarding a surgeon who was placed on probation by the...
A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072
Cryoablation is a well-established technique to treat fibroadenomas. Pilot studies suggest this could be an effective non-surgical treatment for breast cancer. American College of Surgeons Oncology Group Z1072 is a phase II trial exploring the effectiveness of cryoablation in the treatment of breast cancers.
A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072
Cryoablation is a well-established technique to treat fibroadenomas. Pilot studies suggest this could be an effective non-surgical treatment for breast cancer. American College of Surgeons Oncology Group Z1072 is a phase II trial exploring the effectiveness of cryoablation in the treatment of breast cancers.
A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072
Cryoablation is a well-established technique to treat fibroadenomas. Pilot studies suggest this could be an effective non-surgical treatment for breast cancer. American College of Surgeons Oncology Group Z1072 is a phase II trial exploring the effectiveness of cryoablation in the treatment of breast cancers.